الوصف
Type: Tablets
Company: HIKMA PHARMA , EGYPT
Use:Antihypertensive
Active constituent: AMLODIPINE
About Amlodipine
Calcium Channel Blocker, Anti hypertensive,anti angina.
Mechanism of Action of Amlodipine
Amlodipine is a second generation dihydropyridine Ca channel blocker. It exerts it`s antihypertensive, antianginal actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .It markedly relax arterioles and milder effects on veins. They do not compromise haemodynamics and cerebral and renal perfusion.
Indications for Amlodipine
1.Hypertension
2.Prinzmetal`s angina
3.Stable angina
المراجعات
لا توجد مراجعات بعد.